The Urology Center of Spartanburg is one of the best urology hospitals in the Carolinas. Providing quality medical services with state of the art equipment by urology specialists. ... Patient Portal. 391 Serpentine Drive, Spartanburg, SC 29303. 864-585-8221 | 800-585-8221Physicians‧New Patients‧Procedures Offered‧Featured Services‧Patient Education‧Women's Health.