- Similac® 360 Total Care® is the first and only infant formula with a blend of five different human milk oligosaccharides[1] (HMOs) across the three categories of HMOs in breast milk[2], the closest prebiotic blend to that of breast milk and previously only available to infants who are breastfed - Similac 360 Total Care with five HMOs is designed to support babies' developing immune system ....