Oct 1, 2021 • Administrative / Digital Tools. As a reminder, effective November 1, 2021, EnrollSafe will replace CAQH Enrollhub as the electronic funds transfer (EFT) enrollment portal for Anthem Blue Cross and Blue Shield (Anthem) providers.As of November 1, 2021, CAQH Enrollhub will no longer offer EFT enrollment to new users. CAQH Enrollhub is the only CAQH tool being decommissioned..