Memorial Sloan Kettering Cancer Center's main hospital is located at 1275 York Avenue, New York, NY, between 67th and 68th streets. For general information, call Memorial Sloan Kettering at 212-639-2000, 24 hours a day, seven days a week. To make an appointment, call us at 800-525-2225, Monday through Friday between 8:30 AM and 5:30 PM ET..