Emory Gynecology & Obstetrics 7/16/2013 VULVAR AND VAGINAL BIOPSY What is a vulvar/vaginal biopsy? A vulvar/vaginal biopsy takes one or more samples of tissue from the vulva or vagina. The vulva is the outer parts of the female genitals, including the labia, which are often called the lips, and the clitoris..