Liver disease in cystic fibrosis

Genetic factors in cystic fibrosis-associated liver disease. So far, more than 2000 mutations of the CFTR gene have been discovered, and these can be divided into five classes based on their impact on the CFTR protein function. The most common mutation, occurring in about 60-70% of patients with CF, is F508del, which dominates in Europe (including Poland) and North America..

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