Introduction. TFE3-translocation renal cell carcinoma (TFE3-tRCC) is a rare subtype of kidney cancer, characterized by Xp11.2 translocations resulting in TFE3 fusion with various partner genes. To date, more than 20 partner genes have been identified in fusions with TFE3, including SFPQ, ASPSCR1, NONO, PRCC, RBM10, MED15, etc. Due to the variety of partners and fusion structures, the function ....