Suzanne M. de la Monte, ... Miran Kim, in Molecular Nutrition and Diabetes, 2016. 2.7 ALD Mechanisms: Increased Intestinal Permeability (Figure 2). In humans, ethanol administration and ALD are associated with increased intestinal permeability 77 and endotoxemia, reflecting impairment of the intestinal epithelial barrier and enhanced bacterial translocation. 78 Likewise, chronic ethanol ....