Pathophysiology of Portal Hypertension and Esophageal Varices

1. Introduction. Esophageal varices are the major complication of portal hypertension. It is detected in about 50% of cirrhosis patients, and approximately 5-15% of cirrhosis patients show newly formed varices or worsening of varices each year [1-5].It is a hemodynamic abnormality characterized by sudden bleeding episode; about a third of all patients with esophageal varices show bleeding ....

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