5. 1/5. About Zika. What everyone needs to know about Zika virus. Symptoms, Testing, & Treatment. The most common symptoms of Zika are fever, rash, headache, joint pain, red eyes, and muscle pain. Prevention & Transmission. Zika is spread mostly by the bite of an infected mosquito. Prevent Zika by avoiding mosquito bites.Pregnancy‧Symptoms & Treatment‧Zika in The Us‧About Zika‧Zika Travel Information‧Healthcare Providers.