Cancer Immune Evasion Through Loss of MHC Class I Antigen ...

The MHC Class I Pathway of Antigen Presentation. To understand some of the mechanisms by which many cancers evade immune surveillance, it is necessary to first understand the MHC I pathway of antigen presentation (Figure 1).This pathway is the mechanism that allows CD8 T cells to identify cells producing "foreign" proteins, such as ones from viruses in infected cells or mutant genes in ....

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