OneDrive encrypts data when in transit and when at rest. This FIPS 140-2 compliant encryption is done using 256-bit AES. The only way to be HIPAA compliant when using OneDrive is subscribing to OneDrive business packages starting from the Office 365 Business Essentials at $6 per user, per month to Office 365 Enterprise E5 at $35 per user, per ....